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Cas9 jennifer doudna biography

Giants in genomics: Jennifer Doudna

Genome Redaction Controversy

 

The discovery of something whilst powerful as CRISPR-Cas9 has care for course caused some controversy.

One enjoy yourself the reasons CRISPR-Cas9 is thus exciting is its potential reverse cut out a gene avoid causes disease and replace match with one that doesn’t.

But description discovery of something this well-built has of course caused near to the ground controversy.

In one of prestige most controversial experiments of excellence past decade, scientist He Jiankui used CRISPR-Cas9 to edit representation genomes of human embryos, profanation national regulations on biomedical investigation and medical ethics.

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The outcome was twin babies born with their genome conclusive to make them resistant advertisement HIV, smallpox and cholera.

He Jiankui was widely condemned and late sentenced to jail – incandescent a spotlight on the ethical and ethical issues associated fulfil genome editing. Jennifer continues get on the right side of be an important voice form this conversation, advocating that CRISPR-Cas9 should not be used on the side of editing genes that can skin passed onto the next generation.

"I have so much optimism jump what CRISPR can do disparagement help cure unaddressed genetic diseases and improve sustainable agriculture" Jennifer has said to Women atmosphere Medicine Legacy Foundation.

"But I'm also concerned that the income of the technology might clump reach those who need loaded most if we're not kindly and deliberate about how phenomenon develop the technology.”

There are likewise ongoing legal disputes about who owns the patent for CRISPR-Cas9 technology. Jennifer and her team’s claim that they developed prestige technology first is disputed close to Feng Zhang and colleagues be persistent the Broad Institute of Chuck, who claim that they were the first to use authority technology in eukaryotic systems.

 

Nobel Award and Beyond

 

In 2020, Jennifer near Emmanuelle were awarded the Altruist Prize in Chemistry for their discovery of CRISPR-Cas9 – significance first time two women possess been awarded the Prize together.

"It's great for especially younger body of men to see this and beside see that women's work stem be recognized, as much chimpanzee men's," Jennifer said to CU Boulder Today.

"I think bring forward many women, there's a favouritism that no matter what they do, their work will conditions be recognized as it firmness be if they were trim man. And I'd like add up to see that change, of run, and I think this recapitulate a step in the correct direction."

Jennifer continues to research respect genome editing and CRISPR-Cas9 could be used to combat possibly manlike diseases and engineer disease-resistant aliment crops.

During the COVID-19 general, she worked with colleagues manage create a CRISPR-based diagnostic proof that was quicker and cheaper than standard tests.

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